Smitten

From our friends at dictionary.com...

Past participle of smite: to deal a blow with or as if with the hand or a hand-held weapon; to inflict a heavy blow on, with or as if with the hand, a tool, or a weapon; to drive or strike (a weapon, for example) forcefully onto or into something else; to attack, damage, or destroy by or as if by blows; to afflict; to afflict retributively; chasten or chastise; to affect sharply with great feeling: He was smitten by deep remorse.

"The population was smitten by the plague."

OR...

adj 1: (used in combination) affected by something overwhelming; "conscience-smitten"; "awe-struck" [syn: stricken, struck] 2: marked by foolish or unreasoning fondness; "she was crazy about him"; "gaga over the rock group's new album"; "he was infatuated with her" [syn: crazy, dotty, gaga, enamored, infatuated, in love, soft on(p), taken with(p)]

Yup. That about sums it up.